Adult still’s disease Tag Archives

Macrophage Activation Syndrome: A Nearly Fatal Presentation, and Review of Diagnosis and Treatment Guidelines

Macrophage Activation Syndrome

Article Abstract Introduction: Macrophage activation syndrome (MAS) is a rare but life-threatening systemic inflammatory complication, usually arising from superimposed viral infections or flares of underlying rheumatological conditions. It is characterized by an uncontrolled immune response, involving the expansion of T-Cells, Macrophages, and the hypersecretion of pro-inflammatory cytokines. The pathophysiology of this disease is not fully understood, and the diagnostic criteria have been debated. In 2016, …